Description

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Overview

Brand name: Prosom
Drug class: Benzodiazepine hypnotic
Primary use: Insomnia (short-term)
Mechanism: Enhances the effect of GABA, a calming neurotransmitter in the brain, leading to sedation and relaxation.

How It Works

Estazolam binds to benzodiazepine receptors on the GABA-A complex in the central nervous system. This increases inhibitory signaling, which:
Reduces brain activity
Promotes sleep onset
Helps maintain sleep during the night

Indications

Estazolam is prescribed for:
Difficulty falling asleep (sleep-onset insomnia)
Frequent nighttime awakenings (sleep-maintenance insomnia)
It is generally intended for short-term use due to the risk of tolerance and dependence.

Dosage (General Medical Guidance)

Typical adult doses are taken once at bedtime
Lower doses are usually recommended for:
Older adults
Patients with liver impairment
Those sensitive to sedatives
Dosage should always be determined by a healthcare professional.

Side Effects

Common side effects:
Drowsiness
Dizziness
Fatigue
Headache
Coordination problems
Less common but serious effects:
Memory impairment
Confusion
Depression or mood changes
Complex sleep behaviors (e.g., sleepwalking)